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If you have a personal or family history relevant to medullary thyroid carcinoma, or related endocrine syndromes, this needs explicit clinician discussion before use

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54 , 55 , 56 , 57 , 58 , 59 , 60 , 61 , 62 Other studies ( n = 3465) found that metformin (15002000 mg/day) improved insulin sensitivity with or without COCPs after 6 months, 62 , 63 but had no consistent impact on body mass index (BMI), inflammatory markers, or androgens, 60 , 64 and was linked to hypoglycaemia in some cases

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Single images of cells were acquired to measure the number of docked granules

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