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When applied topically or incorporated into cosmetic formulations, the Pure Copper peptide complex binds to cellular receptors on fibroblasts, triggering a cascade of regenerative processes
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Importantly, the disease causing I148M variant was a gain of function for the interaction with ABHD5 and inhibition of lipolysis, and could promote TAG accumulation in an ABHD5-dependent manner (70)
Importantly, the hiPSC line CRL S23 that did not pass the EP screen, i.e
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