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Reinitiation Criteria: Clinicians should consider increasing the dose or reinitiating therapy if a patient experiences more than 5% weight regain

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"Long-term acetyl-L-carnitine treatment in Alzheimer's disease." Neurology 1991;41(11):1726-32

doi: 10.2337/dbi18-0008 48 JastreboffAMAronneLJAhmadNNWhartonSConneryLAlvesBet al

People who are overweight or obese have a higher risk of getting 13 types of cancer, and the risk increases the longer a person is overweight and the more excess weight they gain

Marcus's protocol was a daily subcutaneous injection administered at bedtime