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Glucagon-like peptide-1 (GLP-1) is a naturally occurring hormone produced in the intestines that plays a crucial role in regulating blood glucose levels and appetite

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Additionally, in high-fat-diet-induced obese mice, miR-194 overexpression through transcription factor 7-like 2(Tcf7l2) and forkhead box a1(Foxa1) inhibits proglucagon ( Gcg) and Pcsk1 gene transcription, ultimately suppressing GLP-1 synthesis in L-cells [33]

Effects of cholecystokinin (CCK-8) on two classes of gastroduodenal vagal afferent fibre

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