Commonly Reported Side Effects (across GLP-1 medication users generally): Nausea (often most pronounced when starting or increasing the dose) Vomiting Diarrhea Constipation Abdominal discomfort Headache Fatigue These side effects are often most noticeable during the initial weeks of treatment and during dose escalation periods
If REPATHA is administered during pregnancy, healthcare providers should report REPATHA exposure by contacting Amgen at 1-800-77-AMGEN (1-800-772-6436) or Data Animal Data In cynomolgus monkeys, no effects on embryo-fetal or postnatal development (up to 6 months of age) were observed when evolocumab was dosed during organogenesis to parturition at 50 mg/kg once every 2 weeks by the subcutaneous route at exposures 30- and 12-fold the recommended human doses of 140 mg every 2 weeks and 420 mg once monthly, respectively, based on plasma AUC
Available from: 291 WHO (2022)
o Protein-rich foods: Glutathione is made up of amino acids, so consuming foods that are high in protein can help boost glutathione production
Treat cardiovascular risk according to NICE lipid modification guidance (NG238)
A., Kristrom, B., Rosberg, S., Svensson, B
