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Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer

[DOI] [PMC free article] [PubMed] [Google Scholar] 45.Burmeister MA, et al

Circulation 150, 17811790

This gradual escalation allows your body to adapt to GLP-1 receptor activation while minimizing gastrointestinal side effects and optimizing hunger suppression

Studies with rodents have shown that Wegovy and similar medications can cause thyroid tumours, but it's unclear if this applies to humans

Accordingly, a cohort study found no association between the exposure to GLP-1R agonists and diabetic retinopathy, and in fact GLP-1R agonists were found to even decrease the risk of diabetic retinopathy by 33% when compared to new-users of insulin (Douros et al., 2018)