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While high doses administered over a short duration can induce symptoms such as lethargy, decreased food consumption, and weight loss in these animals, no significant mortality has been observed within specific dosage limits (Mihailovi et al., 2013)

doi: 10.4103/0378-6323.98071

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a two-way ANOVA with repeated measures indicated that all time points for the I nmol dihexa group were different from the scopolamine group, which received vehicle (aCSF) instead of dihexa (***p .001)