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Al-Chalabi A, Jones A, Troakes C, King A, Al-Sarraj S, van den Berg LH

Most subcutaneous protocols use 250500mcg per injection

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This widespread distribution suggests potential mechanisms for migraine reduction: stabilized blood glucose reduces metabolic stress on neurons, decreased inflammation lowers migraine trigger sensitivity, and improved vagal tone may enhance parasympathetic regulation of pain signaling

While these drugs are considered to be safe, more studies are pending about their possible long-term effects, and they commonly have short-term side effects like nausea, constipation, or diarrhea.

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