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[DOI] [PubMed] [Google Scholar] 9.Schafer F.Q., Buettner G.R

No increased risk was seen with shorter ( 15 mL/min/1.73 m 2 , as chlortalidone is the only thiazide-like diuretic to demonstrate efficacy in people with advanced CKD [115]

In addition, glutamatergic synaptic dysfunction (synaptopathy) within the Vmes leads to profound network failure

With aging, bone resorption gradually surpasses bone formation, resulting in bone loss

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These effects include energy metabolism, mitochondrial homeostasis, epigenetic regulation, endocrine regulation, inflammation and immune homeostasis, signal transduction, and neuromodulation (Fig