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There are common side effects, she added - some people can feel bloated or uncomfortable while taking GLP-1s, but often say they can put up with it while Mounjaro commonly causes digestive issues when starting out or increasing a dose, which often subsides

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In persons who are overweight or obese, lean mass contributes only ~2030 percent to total weight loss.6 It should be noted that a 10 percent weight loss can result in a 1-2 percent loss of bone mineral density (BMD)

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Patients with normal or near-normal BMI often qualify for GLP-1 therapy based on type 2 diabetes diagnosis, cardiovascular risk factors, or metabolic markers indicating therapeutic benefit

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