[19] All adverse events including musculoskeletal complaints must be recorded and assessed for potential relatedness to the investigational product by the trial team
Peripheral immune cells, such as macrophages and T lymphocytes, can infiltrate the CNS during chronic inflammation
[1] [7] Other notable effects include injection site reactions beyond pain (erythema, pruritus, induration in 13% of patients), increased heart rate (particularly with liraglutide), gallbladder disease (including gallstones and cholecystitis), and potential dehydration-related acute kidney injury
Original studies that did not investigate pain as a primary and/or secondary outcome were excluded
Specific issues documented include patients charged for medication they never received, difficulty obtaining refunds after cancellation, and wrong doses shipped without resolution
Shanghai, China)