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LPS, an endotoxin produced by Gram-negative bacteria, interacts with immune cells in the bloodstream, upregulating the expression of pro-inflammatory cytokines (e.g., tumor necrosis factor- (TNF-) and interleukins) and systemic inflammation (55)

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Sikiric et al., 2016) centrally mediated counteraction of the L-NAMEinduced catalepsy as well as BPC 157, L-NAME, L-arginine, and NO-relation, in the suited acute and chronic rat behavioral models resembling positive-like symptoms of schizophrenia (Zemba Cilic et al., 2021)