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Typically self-administered as a simple, subcutaneous injection

Therefore, the sponsors concluded that clinically significant DDIs mediated by direct inhibition of CYP enzymes or transporters are unlikely to occur with the administration of GLP-1 RAs and a dual GLP-1/GIP RA

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Importantly, many of the models discussed above can be adapted by incorporating experimental design features that simulate aspects of vascular pathology, thereby enabling the development of MD models

Sequences of primers for qRT-PCR are listed in Supplementary Table 2