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Those supplementing with 1,200 mg of CoQ10 per day for 60 days showed decreased oxidative stress ( Moreover, supplementing with CoQ10 can help increase power during exercise and reduce fatigue, both of which can improve exercise performance ( Summary: Exercise performance can be affected by oxidative stress and mitochondrial dysfunction

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In some research contexts, periodic breaks may actually enhance outcomes by allowing receptor upregulation during rest periods, improving responsiveness when dosing resumes