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Gamma-glutamyl transpeptidase accelerates tumor growth and increases the resistance of tumors to cisplatin in vivo
When activated, AMPK may help: Reduce the production of cholesterol and triglycerides (fats) Improve energy use Encourage the body to burn stored fat These metabolic effects may partly explain why berberine shows some promise in weight-related outcomes
GHK inactivated damaging free radical by-products of lipid peroxidation, such as 4-hydroxynoneal, acrolein, malondialdehyde, and glyoxal, protecting cultured skin keratinocytes from ultraviolet (UV)-radiation [31]
Pharmacological modulators Among pharmacological modulators, the small-molecule HSP72 activator BGP-15 has shown notable promise in both preclinical studies and early-phase clinical trials
It has an extra electron that it can "donate" to a free radical
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