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Immune challenges : Together they support balanced immune responses and viral defense

Of relevance, recent evidence indicates that SAM exerts anti-inflammatory effects by reducing the expression of the proinflammatory cytokine tumor necrosis factor-alpha (TNF) and increasing the expression of the anti-inflammatory cytokine interleukin 10 (IL-10)

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These results in the conversion of NO to various reactive nitrogen species which include nitrosonium cation (NO + ), nitroxyl anion (NO ) and peroxynitrite (ONOO ) (Table 2)