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Modifying a workout due to fatigue 31 or choosing different foods due to nausea 73 should be seen as strategic adaptations to maintain long-term adherence and progress, rather than setbacks

This comes directly from the clinical trial design, and four weeks is generally sufficient for most people to adapt to each new dose level before moving up

After reaching your goal weight: We don't yet know what the maintenance strategy will be once you've achieved your weight loss goals

doi: 10.1210/en.2011-0174 82 KanoskiSERupprechtLEFortinSMDe JongheBCHayesMR

River Crossing YMCAs Healthy Lifestyles Pathway program is a free, 12-week program focusing on weight loss and chronic disease prevention in adults

Rapid improvement in glucose control has been associated with transient worsening of retinopathy, which has been observed in GLP-1 trials