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Notably, excess hemin exposure exacerbates the disease severity of SCD 19,20 and heme-scavenging strategies such as intravenous infusion of hemopexin are propective 21,22

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Wojciechowski AM, Bell BA, Song Y, Anderson BD, Conomikes A, Petruconis C et al (2024) Inducible RPE-specific GPX4 knockout causes oxidative stress and retinal degeneration with features of age-related macular degeneration

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