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In isolated mitochondria and in vitro Erv1 can transfer electrons either directly to oxygen or via cytochrome c and complex IV of the respiratory chain (Figure 7A)

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BioMed Res Int 2020:112 Ackler S, Mitten MJ, Foster K, Oleksijew A, Refici M, Tahir SK, Xiao Y, Tse C, Frost DJ et al (2010) The Bcl-2 inhibitor ABT-263 enhances the response of multiple chemotherapeutic regimens in hematologic tumors in vivo