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A personal or family history of medullary thyroid cancer or MEN2 is a class contraindication

& Chang, L.Y

Bioresource Technology, 386 , 129534

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Demographic projections suggest that by 2050, annual cancer incidence could rise to 35 million cases worldwide

Also a lack of B12 damages the myelin sheath which wraps around our nerves so deficiency is frequently associated with neurological problems