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Diselenide bonds enhance efficacy via ROS generation, while Pt(IV) prodrugs are reduced to active Pt(II) by GSH, overcoming cisplatin limitations

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Researchers at the University of Vienna found that lower L-Carnitine plasma levels lead to a down-regulation of the expression of certain enzymes involved in fatty acid metabolism, namely CPT1, CPT2 and CRAT

doi: 10.1007/s11916-022-01086-y

Individual tolerance often determines optimal dosing, with some users finding 8mg provides excellent results with fewer side effects while others tolerate and benefit from 12mg dosing

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