Pathophysiological and diagnostic implications of cortical dysfunction in ALS
*Correspondence: Luhua Lai, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers
USA 113 , 47774782 (2016)
In healthy individuals, CBF is tightly coupled to the metabolic demands of neurons (Claassen et al., 2021), however, it is unclear whether reduced CBF in ADRD is a cause or consequence of cerebral hypometabolism
Certain medical conditions, such as kidney problems or certain allergies, may require caution or adjustments in the treatment plan
Product Specifications 5-amino-1MQ is a small molecule that blocks the activity of the enzyme called nicotinamide N-methyltransferase (NNMT)