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BRCA is a systemic and complex disease, and what we briefly discuss here may involve many pathogenic factors

Patients typically begin at a lower dose and increase gradually every four weeks to minimize gastrointestinal side effects and maximize tolerability

During the screening process, 32 patients were excluded because of severe comorbidities,25 patients with history of malignancy were excluded and another 30 were excluded due to incomplete follow-up data

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These variants do not determine your medication outcome but can highlight which metabolic systems may be influencing your response

Gogarten, J.P