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Biologics [e.g., TNF- inhibitors (etanercept), IL-6R blockers (tocilizumab)]: Effective in 60 - 70% of patients but incur prohibitive costs ($20,000 - 50,000 annually), limiting accessibility (only 10 - 20% treated in low-resource settings) (5, 6)

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Dulaglutide and renal outcomes in type 2 diabetes: An exploratory analysis of the REWIND randomised, placebo-controlled trial

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These broadened prescribing criteria for Ozempic mean that more people will experience severe side effects from the drug

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While these are different trials with different populations, the triple-agonist mechanism appears to produce faster and slightly greater weight loss

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