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It is worth noting that, to eliminate interference, only GLP-1RA monotherapy was included in this study, that is, primary suspect DRUG (PS) was screened out under the ROLE_COD project of the DRUG file, and ensure that drugs labeled Secondary Suspected drug(SS) and Concomitant drugs(C) corresponding to no other GLP-1RA

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Directly, semaglutide has not been shown to harm kidneys and cardiovascular outcome data suggests potential kidney-protective effects in patients with type 2 diabetes.[11] Indirectly, GI side effects that cause dehydration can strain renal function in patients with pre-existing impairment

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