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261265 Therefore, by inducing pro-inflammatory adhesion molecules and chemokines, hypoxia causes the accumulation of macrophages in the kidney that produce profibrotic cytokines such as transforming growth factor and activate renal fibrobalsts

Your diet is another major factor

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First few months: This is typically the active titration phase - providers adjusting the dose based on tolerance and response, GI side effects (when present) often diminishing, and more visible weight changes becoming apparent for patients who respond to treatment

Be sure to discuss your health history and the medications you take with your doctor

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