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The primary objective was to evaluate the impact of GLP-1 RAs on DED in patients with T2DM, comparing ocular parameters between cases and controls groups

The affected drugs are listed below

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Solution: Use at least 250mcg per injection

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Attaching a fatty acid via a chemical linker to a specific residue on an already-assembled peptide requires controlling the proportion of conjugated versus unconjugated species, detecting and controlling free fatty acid or linker impurities, and monitoring for di- or poly-modification at unintended sites