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Here's what the clinical data says about it

the membranes were then washed several times with water and TBS (PBS, 0.05% Tween-20), a 1 :5000 dilution of horseradish-peroxidase conjugated goat anti-rabbit antiserum was added, and the membranes further incubated for 1 h at room temperature

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doi: 10.18632/aging.205369 150 HuY.FryattG

For instance, chemical synthesis is used for vitamin b1 and b6, while as, fermentation method is employed to get vitamin b12

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