Frailty and Risk of Fractures in Patients With Type 2 Diabetes
The dual GIP/GLP-1 mechanism appears to be more effective than GLP-1 alone, which is why researchers continue developing multi-receptor agonists
One suggested practice to managing GI AEs is the Three Es method, which comprises 1) education and explanation, 2) escalation to an appropriate dose, and 3) effective management of GI AEs
DOI:10.1097/psy.0b013e3181d9523c
For myocardial infarction, GLP-1RAs alleviate and repair MI via SIRT1/Parkin/mitophagy, insulin-like growth factor-1/2 and upregulating -estrogen receptor
While its primary use is in managing seizures and migraines, topiramate also affects pathways in the brain that influence appetite and how things taste