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In another study, oral administration of sertraline was found to cause testicular DNA damage and acute testicular injury in male albino rats, as evidenced by significant degeneration and necrosis of germ cells within the seminiferous tubules, as well as interstitial edema and vascular congestion

Those with kidney issues or certain chronic conditions should consult a physician first.

Ogrodnik M, Miwa S, Tchkonia T, Tiniakos D, Wilson CL, Lahat A, et al

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Cu-binding proteins, such as mitogen activated protein kinase 1 (MEK1) and UNC-51-like kinases 1 and 2 (ULK1/2), facilitate signal cascade activation, promoting tumorigenesis (137)