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When osteoclast activity exceeds osteoblast (bone-building) activity the net result is loss of bone density.' Research supports this, as one trial found that taking semaglutide (one form of GLP-1) was associated with lower bone density and an increased rate of bone breakdown

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Move from a 20% LAA serum to a 10% version, or switch to a vitamin C derivative that works at higher pH

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But some people may have some mild digestive upset