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While these drugs offer many benefits, they also come with significant downsides

Those studies will make it easier to tailor recommendations and quantify expected outcomes for individuals

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Only one of the trials included in the systematic review used the next-generation GLP-1 agonist semaglutide to treat obesity in adolescents aged 1218 years, and none used the combined GLP-1 and glucose-dependent insulinotropic peptide agonist, tirzepatide

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