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Functioning as a transcription factor, the c-Myc upregulates the transcription of PD-L1, MCT1, glycolytic enzymes, and cell cycle accelerators
Glutathione binds to the enzyme, hindering the metabolic pathway of melanin, preventing it from producing dark pigmented melanin or eumelanin, and will instead bring about light-pigmented melanin or phaeomelanin
Prevention: Follow your provider prescribed titration schedule
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Oh JE, Kim SN