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GERD occurs when acid reflux happens repeatedly over time, the Mayo Clinic says

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Basic fibroblast growth factor (bFGF) protects hippocampal and cortical neurons against glutamate toxicity by changing the expression of -methyl-D-aspartic acid (NMDA) receptors and antioxidant enzymes like superoxide dismutases and glutathione reductase [124]

Controversy: Whether current data justify clinical use in fertility, given limited human trials and mechanistic gaps

for generalised pruritus, non-sedating antihistamines such as cetirizine or loratadine and unperfumed emollients may provide relief