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AOD-9604 is the most studied version: a Phase 2b obesity trial reported it was well tolerated with a safety profile comparable to placebo and no rebound weight gain, and it doesnt alter IGF-1 or glucose (BioSpace)

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Schedule regular follow-ups (every 46 weeks initially) to review weight, blood glucose, blood pressure, gastrointestinal tolerance, and any adverse effects

The melanocortin 5 receptor (MC5R) appears to be distributed across multiple tissues, although what role it might serve remains unclear

Though costs have come down since GLP-1s such as Ozempic and Wegovy became available for weight loss, they still typically cost hundreds a month, said Dr

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