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PMID: 41069706 PMCID: PMC12504844 Weisberg, Fraser

Prognosis of LM The exact percentage of cases of LM that progress to LMM is unknown, but based on studies published to date, progression rates would appear to be highly variable, ranging from 5% to 50%.3,33,34 No clinical, histologic, or biologic predictors of malignant transformation have been identified

Obesity is considered a chronic condition so patients should expect to be on the medicine long term, like they would with a blood pressure medicine

This association becomes particularly pronounced after 1 to 3 years of treatment