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Summary of the Evidence The literature search identified a total of 10 phase III trials from the SURPASS trial program (Table 1)

B12 supports energy levels, metabolism, immune health, and nerve function

The shared biological properties of exendin-4 and human GLP-1 probably stem from their primary and secondary structures, but exendin-4 is naturally resistant to degradation by the DPP-4 enzyme, attributed to the presence of glycine at position 2, resulting in an intravenous half-life of approximately 30 minutes (85)