Diabetes duration and control: Longer duration of diabetes and poor glycemic control prior to starting semaglutide may increase vulnerability to eye complications
current medication management strategy is overmedicating glycaemic control and causing both the liver to release stored glucose and Mrs ABI to graze
Efficacy of GLP-1 Receptor Agonists on Weight Loss, BMI, and Waist Circumference for Patients With Obesity or Overweight: A Systematic Review, Meta-analysis, and Meta-regression of 47 Randomized Controlled Trials
Cancer 126, 14211431
Angiogenesis: Research has discussed vessel formation, endothelial function, and vascular repair pathways
For example, in colorectal cancer, CUL5 interacts with Endoplasmic Reticulum Protein 29 (ERp29), a protein involved in endoplasmic reticulum stress (ERS), and their cooperation promotes cancer cell invasion, migration, and epithelial-mesenchymal transition (15)