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Inactivated KCs maintain NF-B in the cytoplasm via the inhibitory KB protein (IKB), whereas in activated KCs, the inhibitory KB kinase (IKK) phosphorylates IKB, releasing NF-KB into the nucleus in response to various extracellular stimuli, such as LPS and complement C3/C5

The symptoms that were listed (oligomenorrhea, hirsutism, biochemical and functional hyperandrogenism, etc.) were hyperandrogenism and others

Intranigral LPS administration produces dopamine, glutathione but not behavioral impairment in comparison to MPTP and 6-OHDA neurotoxin models of Parkinsons disease

This, in turn, promotes weight loss

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Serious but Rare Side Effects: Pancreatitis : There is a slight risk of developing pancreatitis