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No, results appear gradually over several weeks as the skin renewal cycle progresses
The brain does not exist in isolation from the kidneys, the heart, or the metabolism
Microorganisms (2019) 7:14
CrossRef Longitudinal effects of oneleg standing time on neuropathy outcomes in association with glycemic control in nonelderly patients with type 2 diabetes Kazuhiro Sugimoto, Takashi Sozu, Takehiko Hoshino, Yuko Watanabe, Akira Tamura, Toshiro Yamazaki, Setsu Ohta, Susumu Suzuki, Takuro Shimbo Journal of Diabetes Investigation.2022
Begara-Morales et al
Starting at 250-300mcg regardless of body weight, then adjusting based on response, often works better than jumping to weight-based higher doses
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