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doi: 10.3389/fimmu.2025.1578940 Received 18 February 2025 Accepted 24 March 2025 Published 10 April 2025 Volume 16 - 2025 Edited by Fabrizio Fontana, University of Milan, Italy Reviewed by Bjrn Steen Sklhegg, University of Oslo, Norway Josephine Anthony, Meenakshi Academy of Higher Education and Research, India Updates Copyright 2025 Fang, Gao, Jiang, Li and Li

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Cardiometabolic outcome trials Older women taking orlistat had improved biventricular diastolic function and beneficial restructuring of their myocardium, producing a lower left ventricular mass, at the end of 6 months, although the cardiac outcomes were likely the result of weight loss rather than independent effect of orlistat [105]