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Khlevner J, Park Y, Margolis KG

Efficacy, side effects, and monitoring of oral cyclosporine in interstitial cystitis/bladder pain syndrome

Berberine has poor natural bioavailability, meaning your body absorbs only a fraction of what you swallow the right absorption enhancers change this considerably

These effects typically decrease as your body adjusts, and your PlexusDx prescriber can adjust your dose pace if side effects become bothersome

You can also cut the suppository into half and use daily if it's too strong or you're looking for a smaller dose

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