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The intracellular proteins could reflect transfer from tumor cells to immune cells through extracellular vesicles, mitochondriaplasma membrane interactions 39 or tunneling nanotubes 40 or they could be artifacts from nonspecific binding due to our use of the monoculture (rather than coculture) no-LaccID negative control for data filtering (Fig

The label does say, regarding the original titration: "To reduce the likelihood of gastrointestinal adverse reactions, escalate dose as described above." That same principle applies to restarting

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