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Semaglutide (Wegovy/Ozempic) is the closest currently available alternative, producing 14-16% average weight loss compared to tirzepatide at 18-22%

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It is currently recommended that all patients with diabetes be screened for advanced fibrosis every 1-2 years

This increase reflects a pattern of growing use of newer GLP-1s, such as Ozempic and Mounjaro, while use of older products, such as Byetta (approved in 2005), Victoza (approved in 2010), and Trulicity (approved in 2014), has declined