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Data Extraction and Quality Assessment Two investigators (Hu and Song) independently extracted the following data by reviewing the full text of each study: first author, year of publication, Clinical Trial Registration Number (NCT ID), trial duration, patient characteristics, sample size, intervention (type of GLP-1 receptor agonist), comparators, and outcomes of interest

Transl Cancer Res

receives funding from Zealand Pharma, Novo Nordisk, Eli Lilly & Co., and Boehringer Ingelheim

Description & Pharmacodynamics Mechanism of Action MT-2 primarily interacts with melanocortin receptors (MC-Rs) : MC-1R : Promotes melanin synthesis , leading to increased skin pigmentation and enhanced UV protection ( 1 )

Shift work as an oxidative stressor

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