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The donation of SAM's methyl group reduces it to SAM-e (S-adenosylmethionine), which reforms homocysteine, and the cycle begins again

The signaling system controlling this balance is remarkably complex

This approach selectively targets pigmentation without causing thermal damage to surround tissues, minimizing the risk of inflammation and post-inflammatory hyperpigmentation

Copper is helpful in small amounts, so the main caution is overuse, and many providers suggest avoiding it at the same time as strong acids or high-strength vitamin C

All in all, limonene has some pros and cons, but - especially if your skin is sensitive - the cons probably outweigh the pros

Risk factors include recent surgery, prolonged immobility, cancer, pregnancy, and genetic clotting disorders