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69% have been using the medication for fewer than two years and 53% expect to discontinue use in less than two more years 77% who had discontinued a GLP-1 medication said they were satisfied with the weight loss they experienced, but 90% were on the drug for less than one year Primary barriers to continued use: 76% note side effects

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Additionally, NSAIDs can affect kidney function by reducing renal blood flow, particularly in patients with pre-existing kidney disease, dehydration, or those taking other medications that stress the kidneys

Essawy AE, El-Sayed SA, Tousson E, Abd El-Gawad HS, Alhasani RH, Abd Elkader H-TAE

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