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Change in VCTE In the random effects model assessing change in VCTE, FGF21 demonstrated a significant standardized mean difference (SMD) of 1.71 (95% CI: 3.11 to 0.31, p = 0.017) compared to placebo, while Resmetirom showed a borderline significant effect with an SMD of 1.68 (95% CI: 3.38 to 0.02, p = 0.053) (Figure 4)

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