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Patients with active scalp infections, certain autoimmune conditions, active malignancy, pregnancy, or unrealistic expectations are typically not candidates and are screened at the consultation

Increased CD38 and PARP activity results in increased hydrolysis of NAD + and NADP +

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When needed, a single aliquot can be thawed for use

Other causes include genetic predisposition, hormonal factors, poor skin care, and even diet (172)