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Animal studies have used subcutaneous and intraperitoneal routes

Peripheral immunological profiling of Parkinsons patients shows increased CD14CD16 monocytes with greater TLR expression, combined with higher plasma LBP and soluble CD14 (sCD14) levels, indicating endotoxin exposure [77]

While its potential as a systemic anti-aging therapeutic is heavily discussed in longevity circles, the optimal delivery method to target the central nervous system has remained speculative